Pravastatin tablets

About pravastatin

Lipids, or fats, are easily stored in your body and serve as a source of energy. Cholesterol is a type of lipid that is made in your liver from the fatty foods that you eat. When the concentration of cholesterol in your blood is too high, it is called hypercholesterolaemia. Although a high level of cholesterol will not make you feel ill, it can cause a problem if left untreated.

People with hypercholesterolaemia can develop small fatty patches called atheroma. These patches develop when excess fat is deposited on to the walls of blood vessels. Over time, these patches can make a blood vessel narrower and this is called atherosclerosis (sometimes referred to as 'hardening of the arteries'). The narrowing reduces the blood flow through the artery and increases the risk of a number of heart and blood vessel diseases, such as heart attack and stroke.

Pravastatin belongs to a group of medicines known as statins (or HMG-CoA reductase inhibitors). It reduces the amount of cholesterol and other lipids made by your body. It does this mainly by blocking the action of a certain enzyme which is needed to make cholesterol. This lowers your risk of heart and blood vessel disease. Pravastatin can also reduce the risk of heart disease in people who have an increased risk of it, even if their cholesterol levels are normal.

Before taking pravastatin

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking pravastatin it is important that your doctor knows:

• If you are pregnant, trying for a baby or breastfeeding.

• If you have any problems with the way your liver works, or if you have ever had a disease which has affected your liver.

• If you have an underactive thyroid gland.

• If you have a problem with unexplained muscle aches or pains, or if you (or a close relative) have ever had a muscle disorder.

• If you regularly drink large amounts of alcohol.

• If you have any problems with the way your kidneys work.

• If you have ever had an allergic reaction to a medicine.

• If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.

How to take pravastatin

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about pravastatin and will provide you with a full list of the side-effects which you may experience from taking it.

• Take pravastatin once each day, in the evening. There are several strengths of tablet available, so your doctor will tell you which strength is right for you. Swallow the tablet with a drink of water. It can be taken either before or after food.

• If you forget to take a dose, leave out the missed dose but make sure that you remember to take your next dose when it is due. Do not take two doses together to make up for a forgotten dose.
  

Getting the most from your treatment

• Try to keep your regular appointments with your doctor. This is so that your doctor can check on your progress. You will need to have blood tests from time to time. These are to measure your cholesterol level and also to check that your liver has not been affected by taking pravastatin.

• Your doctor will give you advice about eating a healthy diet, cutting down on the amount of alcohol you normally drink, reducing the amount of salt in your diet, stopping smoking and taking regular exercise. Following this advice will also help you to reduce your risk of developing heart and blood vessel disease.

• Women taking pravastatin must avoid getting pregnant. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner.

• Treatment with pravastatin is usually long-term unless you experience an adverse effect. Continue to take the tablets unless you are advised otherwise by your doctor.

Can pravastatin cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with pravastatin, although these tend to be mild. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for further advice.

How to store pravastatin

• Keep all medicines out of the reach and sight of children.

• Store in a cool, dry place, away from direct heat and light.
  

Important information about all medicines